Research Fellow Kai Kudo presented at the 98th Annual Meeting of the Japanese Biochemical Society.

The 98th Annual Meeting of the Japanese Biochemical Society

• Date: November 5, 2025
• Venue: ICC Kyoto
• Title: Elucidation of the Renal Protective Mechanisms of CD5L via Regulation of Lipid Metabolism and Oxidative Stress

Vice director Arai gave an oral presentation at the 98th Annual Meeting of the Japanese Biochemical Society.

The 98th Annual Meeting of the Japanese Biochemical Society

• Date: November 4, 2025
• Venue: ICC Kyoto
• Symposium: The Blessing and Curse of Food: Diet-Driven Pathophysiology in Modern Society
• Title: Overnutrition-Induced “Self as Non-Self”: Insights from a Primordial Immune Sensor

Vice director Arai gave an oral presentation at 2nd Symposium on the Immunobiology of Pattern Recognition Receptors.

2nd Symposium on the Immunobiology of Pattern Recognition Receptors

• Date: October 1, 2025
• Venue: Olympic Museum, Lausanne, Switzerland
• Title: CD5L as a noncanonical PRR: SRCR-mediated recognition of altered self and dynamic ligand gating in modern inflammatory contexts

Director Miyazaki presented as a symposium speaker at The 31st Annual Meeting of the Japanese Society of Hemodiafiltration.

The 31st Annual Meeting of the Japanese Society of Hemodiafiltration

• Date: September 27, 2025
• Venue: Kobe International Conference Center
• Theme: Oxidative stress in dialysis patients
• Title: Toward the development of a new-generation therapy targeting advanced and end-stage CKD by AIM

Vice director Arai presented at The 23rd Awaji International Forum on Infection and Immunity.

 The 23rd Awaji International Forum on Infection and Immunity

• Date: September 11, 2025
• Venue: Awaji Yumebutai International Conference Center

Senior Research Fellow Natsumi Maehara gave an oral presentation at the 66th Annual Meeting of the Japanese Society of Neurology.

The 66th Annual Meeting of the Japanese Society of Neurology

• Date: May 24, 2025
• Venue: Osaka International Convention Center
• Title: AIM/CD5L promotes phagocytic removal of amyloid-beta thereby improving Alzheimer's disease

A research paper, in collaboration with Prof. Miyake from The Institute of Medical Science, The University of Tokyo, has been published in a scientific journal.

Sato R, Liu K, Shibata T, Hoshino K, Yamaguchi K, Miyazaki T, Hiranuma R, Fukui R, Motoi Y, Fukuda-Ohta Y, Zhang Y, Reuter T, Ishida Y, Kondo T, Chiba T, Asahara H, Taoka M, Yamauchi Y, Isobe T, Kaisho T, Furukawa Y, Latz E, Nakatani K, Izumi Y, Nie Y, Taniguchi H, Miyake K. RNase T2 deficiency promotes TLR13-dependent replenishment of tissue-protective Kupffer cells. J Exp Med. 2025, 222, 20230647.

We are pleased to announce our research paper has been published in a scientific journal.

Yasuda K, Nishijima A, Inoue T, Takagi T, Tanabe K, Minakuchi J, Arai S, Miyazaki T. Release of apoptosis inhibitor of macrophage (AIM) from pentameric IgM in serum predicts prognosis after hemodialysis initiation. Commun Med. 2025, 5, 15.

Vice director Arai gave an oral presentation at The 53rd Annual Meeting of the Japanese Society for Immunology.

The 53rd Annual Meeting of the Japanese Society for Immunology

• Date: December 3, 2024
• Venue: DEJIMA MESSE NAGASAKI
• Title: Structural insights into the IgM-CD5L complex and its impact on resolution of inflammation through DAMPs recognition

Vice director Arai presented at The 47th Annual Meeting of the Molecular Biology Society of Japan.

The 47th Annual Meeting of the Molecular Biology Society of Japan

• Date: November 28, 2024
• Venue: Fukuoka International Congress Center
• Title: Quantification of stress accumulation and understanding novel stress responses through serum protein AIM/CD5L