A research paper, in collaboration with Prof. Miyake from The Institute of Medical Science, The University of Tokyo, has been published in a scientific journal.

Sato R, Liu K, Shibata T, Hoshino K, Yamaguchi K, Miyazaki T, Hiranuma R, Fukui R, Motoi Y, Fukuda-Ohta Y, Zhang Y, Reuter T, Ishida Y, Kondo T, Chiba T, Asahara H, Taoka M, Yamauchi Y, Isobe T, Kaisho T, Furukawa Y, Latz E, Nakatani K, Izumi Y, Nie Y, Taniguchi H, Miyake K. RNase T2 deficiency promotes TLR13-dependent replenishment of tissue-protective Kupffer cells. J Exp Med. 2025, 222, 20230647.

We are pleased to announce our research paper has been published in a scientific journal.

Yasuda K, Nishijima A, Inoue T, Takagi T, Tanabe K, Minakuchi J, Arai S, Miyazaki T. Release of apoptosis inhibitor of macrophage (AIM) from pentameric IgM in serum predicts prognosis after hemodialysis initiation. Commun Med. 2025, 5, 15.

Vice director Arai gave an oral presentation at The 53rd Annual Meeting of the Japanese Society for Immunology.

The 53rd Annual Meeting of the Japanese Society for Immunology

• Date: December 3, 2024
• Venue: DEJIMA MESSE NAGASAKI
• Title: Structural insights into the IgM-CD5L complex and its impact on resolution of inflammation through DAMPs recognition

Vice director Arai presented at The 47th Annual Meeting of the Molecular Biology Society of Japan.

The 47th Annual Meeting of the Molecular Biology Society of Japan

• Date: November 28, 2024
• Venue: Fukuoka International Congress Center
• Title: Quantification of stress accumulation and understanding novel stress responses through serum protein AIM/CD5L

We are pleased to announce our research paper has been published in a scientific journal.

Press release is available in Japanese.

Chen Q, Ishii K, Mori H, Nishijima A, Arai S, Miyazaki T, Rosenthal PB. Cryo-EM reveals structural basis for human AIM/CD5L recognition of polymeric immunoglobulin M. Nat Commun. 2024, 15, 9387.

Vice director Arai will give an oral presentation at The 18th Annual Meeting of the Biomedical Society for Stress Response, Japan.

The 18th Annual Meeting of the Biomedical Society for Stress Response, Japan

• Date: November 2, 2024
• Venue: MIYAZAKI CITIZEN’S PLAZA
• Title: Quantification of stress accumulation using serum protein AIM and its clinical application

Vice director Arai presented at The 22nd Awaji International Forum on Infection and Immunity.

The 22nd Awaji International Forum on Infection and Immunity

• Date: September 18, 2024
• Venue: ROHM Theatre Kyoto

Director Miyazaki to deliver lecture at The 58th Annual Meeting of Japanese Association for Experimental Animal Technologists.

 The 58th Annual Meeting of Japanese Association for Experimental Animal Technologists

• Title: Development of Novel Therapeutics for End-stage Kidney Failure and Uremia through AIM (CD5L)
• Date:October 11, 2024 (Friday)
• Venue: Kitakyushu International Conference Center

Director Miyazaki to deliver lecture at The 33rd Japanese Association for Renal Failure Surgery.

The 33rd Japanese Association for Renal Failure Surgery

• Title: Creation of a new medical treatment for end stage kidney failure with AIM
• Date: July 13, 2024 (Saturday)
• Venue: Hotel Buena Vista, Matsumoto

Vice director Arai presented at EMBO/EMBL Symposium.

EMBO/EMBL Symposium

• Date: June 20, 2024
• Venue: EMBL Advanced Training Centre, Heidelberg, Germany